Build GuidesUpdated June 2026

Best Once Human Builds Guide (PvE & PvP)

Discover the top meta builds for dominating both PvE content and PvP combat.

Overview

Once Human offers a variety of build configurations that cater to different playstyles. Whether you prefer aggressive close-quarters combat or tactical ranged approaches, this guide covers the best meta builds currently dominating the game.

Best PvE Build: Devastator

The Devastator build is optimized for clearing PvE content efficiently, focusing on high damage output against mobs and bosses.

Primary Weapons

  • AR-55 Ursa - Primary weapon for sustained damage
  • SG-45 Wolverine - Secondary for close encounters
  • Cryo Grenade - Crowd control option

Key Stats

  • Strength: 25
  • Endurance: 15
  • Precision: 10

Recommended Perks

  • Rapid Fire - Increase fire rate by 20%
  • Armor Penetration - Ignore 30% enemy armor
  • Adrenaline Rush - Kills restore 10% health

Best PvP Build: Shadow Strike

The Shadow Strike build excels in PvP scenarios, prioritizing burst damage and mobility.

Primary Weapons

  • SMG-9 Viper - High mobility primary
  • Sniper MK-4 Eagle - Long-range precision

Key Stats

  • Agility: 30
  • Precision: 20
  • Strength: 5

Hybrid Build: Balanced Fighter

A versatile build that performs well in both PvE and PvP scenarios.

Primary Weapons

  • AR-55 Ursa - Versatile primary
  • Shotgun SG-45 - Close-range backup

Key Stats

  • Strength: 18
  • Agility: 18
  • Endurance: 14

Stat Allocation Tips

When allocating stats, prioritize your primary damage source. For weapon-based builds, focus on matching stats that boost your weapon type. Always keep at least 10 points in Endurance for survivability.

Armor Recommendations

Endgame armor sets vary by playstyle. The Stalker set provides bonus stealth for PvP, while the Titan set offers maximum protection for PvE boss fights.